The global single-use bioreactors market size was valued at US$ 0.8 billion in 2024, and is projected to reach US$ 2.4 billion by 2031, witnessing a market growth CAGR of 16.6% from 2025 to 2031, according to an analysis by Stratview Research.
Stratview Research, a global market research firm has launched a report on the global single-use bioreactors market which provides a comprehensive outlook of the global and regional industry forecast, current & emerging trends, segment analysis, competitive landscape, & more.
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Market Statistics:
Market Size in 2024: US$ 0.8 billion
Market Size in 2031: US$ 2.4 billion
Growth (CAGR): 16.6% during 2025-2031
Leading Product Type: Stirred-Tank
Leading Cell Type: Mammalian cell
Leading Capacity Type: 50L to 1000L
Leading End-User Type: Biopharmaceutical manufacturers
Leading Region: North America
Forecast Period: 2025-2031
Trend Period: 2019-2023
Base Year: 2024
Number of Segments Covered: 5
Number of Tables & Graphs: 100+
Country-Level Market Assessment: 20
Segment Insights & Market Share Analysis of the Single-Use Bioreactors Market:
The global single-use bioreactors market is segmented based on product type, cell type, capacity type, end-user type and region.
Based on Product type –
- The market is segmented into stirred-tank, rocking, and fixed-bed. Key advantages of stirred-tank bioreactors are their proven scalability, efficient mixing, and widespread familiarity among bioprocessing professionals.
- Their compatibility with a wide range of cell cultures and processes, especially for monoclonal antibody and vaccine production, makes them highly preferred.
Additionally, continuous improvements in impeller design, oxygen transfer, and sensor integration have enhanced their performance, making stirred-tank systems the industry standard in both clinical and commercial manufacturing settings.
Based on the Cell type –
- The single-use bioreactors market is segmented into mammalian cells, microbial cells, and other cells. Mammalian cells dominate the market as they are widely used to produce complex biologics like monoclonal antibodies and vaccines.
- Their ability to perform human-like protein modifications makes them essential for many therapies. The ease of scaling and integration with single-use systems, along with growing demand for biologics, supports their continued dominance and fast growth in the market.
Based on the Capacity type –
- In terms of capacity, the market is segmented into < 50L, 50L to 1000L, and > 1000L. The 50L to 1000L capacity range is ideal for clinical and mid-scale production, widely adopted by CDMOs and biotech firms, and offers faster turnaround with reduced downtime.
- Its flexibility across applications, compatibility with modular cleanroom designs, and overall cost-effectiveness make it the most preferred capacity range, driving its continued dominance in the single-use bioreactors market.
Based on the End-User type –
- The single-use bioreactors market is segmented into biopharmaceutical manufacturers, life science R&D companies & academic research, and contract research organizations & manufacturers. Biopharmaceutical manufacturers dominated the market owing to the increased flexibility, scalability, cost-efficiency, and reduced contamination risks offered by single-use technologies, which completely align with the dynamic nature of biopharmaceutical production.
- Contract Research Organizations (CROs) and Contract Manufacturing Organizations (CMOs) are the fastest-growing end-user type in the single-use bioreactors market owing to the rising trend of outsourcing biopharmaceutical development and manufacturing to reduce costs, increase flexibility, and accelerate time-to-market. Single-use systems align perfectly with the needs of CROs and CMOs, offering rapid changeovers, multi-product flexibility, and lower infrastructure requirements.
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Which Region Shows the Most Promising Growth Forecast and Opportunity?
“North America is expected to remain the leading region for the single-use bioreactors market throughout the forecast period.”
- In terms of region, the market is segmented into North America, Europe, Asia-Pacific, and the Rest of the World. North America has a well-established biopharmaceutical industry, high R&D investment, and the early adoption of advanced bioprocessing technologies. The region is home to several major biotech companies, CDMOs, and research institutions that actively use single-use systems for clinical and commercial-scale production.
- Additionally, supportive regulatory frameworks, a strong focus on biologics and personalized medicine, and the growing demand for flexible and cost-effective manufacturing solutions further drive market growth in North America.
- China is projected to witness the fastest growth in the single-use bioreactors market in the coming years, driven by rising healthcare expenditure, growing biopharmaceutical production capacity, and strong government support for biotech innovation. The region also benefits from the active presence of major industry players, which are expanding their operations and investments in China to meet the surging local demand for advanced bioprocessing solutions.
Single-Use Bioreactors Market Drivers:
Some of the key drivers listed in the report are given below.
- The single-use bioreactors market is propelled by the rising demand for biologics, including monoclonal antibodies, vaccines, and cell & gene therapies.
- These systems enable faster and more cost-effective manufacturing by minimizing the need for cleaning, setup, and validation.
- Their disposable, pre-sterilized components reduce the risk of cross-contamination, making them ideal for multi-product facilities. Additionally, the growing adoption by CDMOs and biotech firms is driven by the flexibility, scalability, and efficiency that single-use technologies offer.
- Ongoing technological advancements, such as integration with automation, single-use sensors, and smart control systems, further enhance their appeal across the bioprocessing industry.
Competitive Landscape: Top Companies in the Single-Use Bioreactors Market:
The market for single-use bioreactors is very competitive and highly consolidated, with the leading players capturing the lion’s share. The major players are actively acquiring smaller companies to strengthen their market position and expand their technology portfolios. This strategy enables leading firms to enhance their product offerings, access new customer bases, and maintain a competitive edge in a rapidly growing and innovation-driven market. The following are the key players in the single-use bioreactors market.
Here is the list of the Top Players (Based on Dominance)
- Sartorius AG
- Thermo Fisher Scientific Inc.
- Danaher Corporation
- Merck KGaA
Note: The above list does not necessarily include all the top players in the market.
What Unique Insights Does This Report Offer?
This report provides comprehensive insights into the market, answering critical questions like
- How big is the sales opportunity?
- Which regions offer the best sales opportunities?
- Which are the most attractive market segments?
- Which are the top players and their market positioning?
- How complex is the business environment?
- What are the factors affecting the market?
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