“Chromatography membrane filters market size stood at US$ 108 million in 2023 and is likely to grow at an excellent CAGR of 10.0% in the long run to reach US$ 218 million in 2030.”
Market Dynamics
Introduction
Global demand for biologics, vaccines, and monoclonal antibodies is growing, so the biopharmaceutical industry has become more dependent on membrane chromatography to initiate purification and separation procedures. This trend boosts demand for chromatography membrane filters. Expansion in the field of gene therapy and cell culture-based manufacturing processes further increases demand for filtration systems since products from cell-based applications and gene therapies depend heavily on membrane filters for purification. Membrane chromatography is recognized as the perfect substitution for column chromatography because it significantly improves chromatography from affinity, hydrophobicity, and ion exchange. The development status of membrane chromatography in membrane matrix and membrane equipment is posing excellent growth opportunities, and the applications of protein capture and purification, virus, monoclonal antibody purification, and water treatment are likely to drive the market in years to come.
Recent Market JVs and Acquisitions:
The chromatography membrane filters market has undergone a few mergers & acquisitions in past years as enterprises strive to augment their market presence and leverage synergies to refine their product offerings and optimize their fiscal outcomes. Some M&A and JVs are:
- Danaher Corporation completed the acquisition of General Electric Company's Life Sciences division in March 2020, under its biopharma business, to create Cytiva. The new company is operating within Danaher's Life Sciences segment.
- Merck’s acquisition of Sigma Aldrich has strengthened its filtration and separation market position and enhanced its Natrix membrane filter technology capabilities.
Recent Product Development:
- Thermo Fisher Scientific has introduced the Thermo Scientific HyPeak Chromatography System to enhance downstream bioprocessing. It will improve the efficiency of both continuous and batch processes while reducing operational costs.
- Sartorius introduced Sartobind Rapid A membranes, which enabled higher throughput and scalability in high-capacity monoclonal antibody capture.
Market Drivers:
Chromatography membrane filter systems have witnessed an accelerated adoption in the biopharma industry as they align closely with bioprocessing practices. Membrane-based capsules are preferred dominantly nowadays for filtration and separation needs during drug production. Research and developments in this market have significantly reduced production costs and increased efficiency. Surging demand from industries like food & beverage, biopharmaceutical, and water treatment applications is expected to drive the growth of the chromatography membrane filters market in the forecasted period.
Challenges:
The risk of contamination at different stages of production is a severe challenge that drives the cost of production. Chromatography membrane filters are designed for single-use applications, which implies they need to be replaced after processing each batch. Hence, multi-use chromatography filters are preferred in applications where the required purity level is low. Currently, the domain of application of chromatography membrane filters is restricted only to biopharma.
Market Segments' Analysis
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Segmentations
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List of Sub-Segments
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Segments with High Growth Opportunity
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By Process Type
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Ion Exchange, Affinity, and HIC
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Ion exchange is the market's dominant and fastest-growing process.
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By Product Type
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Capsules, Cartridges, Cassettes, and Others
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Capsules dominate among product types and are likely to grow the fastest as well.
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By Material Type
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Modified PES, PTFE, Cellulose, Hydrogel, and Others
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Modified PES is the preferred material and is likely to remain dominant in the future.
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By Region
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North America, Europe, Asia-Pacific, and The Rest of the World
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Asia-Pacific leads the chromatography membrane filters market and is also estimated to show robust growth.
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By Process Type
“Ion exchange enjoys the lion’s share in the chromatography membrane filters market owing to its widely adopted application in the biopharma industry. It is likely to maintain its dominance and grow over the forecasted period.”
- Ion exchange has excellent resolution, which is essential for separating molecules according to charge properties. In most biopharma purification, impurities are charged with ions, which makes ion exchange the most used process type.
- Ion exchange generally employs less expensive, less complex buffers than affinity chromatography, which typically demands very expensive, ligand-specific buffers. Cost-effectiveness has also driven ion exchange to lead the market.
- Sartorius, the leader in the chromatography membrane filters market, has significantly focused on developing cation and anion exchange membrane filters, indicating this process type's dominance in the market.
By Product Type
“Capsules are the dominant product of the chromatography membrane filters market. It is likely to maintain its dominance throughout the forecast years.”
- They are compact and ready to use, thus highly convenient for use in labs and production facilities. They require much less time for installation or setup than cartridges or cassettes.
- Capsules are the preferred product for applications like viral clearance and antibody purification due to their higher flow rate, which results in a much lesser turnaround time.
- The use of capsules allows the processing of a much larger batch at the same turnaround time, enhancing efficiency without compromising the extent of purification.
By Material Type
“Modified polyethersulfone (PES) has been the preferred choice to prepare membrane filters since its inception. It dominates the market and is likely to remain dominant during the forecasted period.”
- Modified PES offers versatility in applications and is also compatible with different buffers. It also excels in mechanical strength and thermal stability, enabling filters to withstand faster flow rates.
- PES's water-repelling or hydrophilic nature enhances its water permeability and reduces protein binding, making it ideal for high-flow filtration in biopharma applications.
- Modified PES membranes' chemical resistance and pH tolerance make them versatile. They support applications across a wide range of conditions without compromising filtration quality or membrane durability.
By Region
“Asia-Pacific region is forecasted to be both biggest and fastest-growing region driven by China’s dominant presence.”
- The biopharma industry is booming in Asian countries. India, China, and Japan contribute significantly to drug and vaccine production. Hence, this region is very optimistic for the chromatography membrane filter market.
- Investments in healthcare infrastructure and R&D continue without hindrance in the Asia-Pacific countries.
- Government initiatives have supported indigenous drug production in the post-COVID era, driving the demand for chromatography membrane filters.
- Many countries in the Asia-Pacific region are among the fastest-aging in the world, presenting a significant societal challenge that is accelerating investments and research efforts for innovative medical solutions in the region.
Key Players
It would be fair to say that the market is fairly consolidated, with a few players contributing significantly to it. The leading players in the industry contend with several critical factors, including pricing strategies, service portfolios, regional presence, and other governing parameters. The following are the key players in the chromatography membrane filter market. These big players often engage in mergers and acquisition activities as a key strategy to enhance their portfolios and regional presence.
Here is the list of the Top Players (Based on Dominance)
- Sartorius AG
- Danaher (Cytiva)
- Merck KgaA
- Thermofisher Scientic
- The 3M Company
- Donaldson
- Agilent Technologies Inc.
- Restec Corporation
- Cole Parmer Instrument Company LLC
- GVS Group
Note: The above list does not necessarily include all the top players in the market.
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Report Features
This report provides market intelligence most comprehensively. The report structure has been kept so that it offers maximum business value. It provides critical insights into market dynamics and will enable strategic decision-making for existing market players as well as those willing to enter the market. The following are the key features of the report:
- Market structure: Overview, industry life cycle analysis, supply chain analysis.
- Market environment analysis: Growth drivers and constraints, Porter’s five forces analysis, SWOT analysis.
- Market trend and forecast analysis.
- Market segment trend and forecast.
- Competitive landscape and dynamics: Market share, Service portfolio, New Product Launches, etc.
- COVID-19 impact and its recovery curve.
- Attractive market segments and associated growth opportunities.
- Emerging trends.
- Strategic growth opportunities for the existing and new players.
- Key success factors.
The chromatography membrane filters market is segmented into the following categories:
Chromatography Membrane Filters Market by Process Type
- Ion Exchange (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Affinity (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- HIC (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
Chromatography Membrane Filters Market by Product Type
- Capsule Filters (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Cartridge Filters (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Cassette Filters (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Other Filters (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
Chromatography Membrane Filters Market, by Material Type
- Modified PES Filters (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- PTFE Filters (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Cellulose Filters (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Hydrogel Filters (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Other Filters (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
Chromatography Membrane Filters Market by Region
- North America (Country Analysis: The USA, Canada, and Mexico)
- Europe (Country Analysis: Germany, France, The UK, and Rest of Europe)
- Asia-Pacific (Country Analysis: Japan, China, India, and Rest of Asia-Pacific)
- Rest of the World (Country Analysis: Brazil, Saudi Arabia, and Others)
Research Methodology
- This strategic assessment report from Stratview Research provides a comprehensive analysis that reflects today’s chromatography membrane filters market realities and future market possibilities for the forecast period.
- The report segments and analyses the market in the most detailed manner in order to provide a panoramic view of the market.
- The vital data/information provided in the report can play a crucial role for market participants and investors in identifying the low-hanging fruits available in the market and formulating growth strategies to expedite their growth process.
- This report offers high-quality insights and is the outcome of a detailed research methodology comprising extensive secondary research, rigorous primary interviews with industry stakeholders, and validation and triangulation with Stratview Research’s internal database and statistical tools.
- More than 1,000 authenticated secondary sources, such as company annual reports, fact books, press releases, journals, investor presentations, white papers, patents, and articles, have been leveraged to gather the data.
- We conducted more than 15 detailed primary interviews with market players across the value chain in all four regions and industry experts to obtain qualitative and quantitative insights.
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Company Profiling
- Detailed profiling of additional market players (up to three players)
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Competitive Benchmarking
- Benchmarking of key players on the following parameters: Service portfolio, geographical reach, regional presence, and strategic alliances
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