“Membrane chromatography market size stood at US$ 0.6 billion in 2023 and is likely to grow at an excellent CAGR of 9.7% in the long run to reach US$ 1.1 billion in 2030.”
Market Dynamics
Introduction
The membrane chromatography market is experiencing phenomenal growth due to the increasing demand for biopharmaceuticals and the general advantages of membrane chromatography over traditional technologies. Membranes permit faster processing, lower buffer consumption, and reduced contamination risks. Cleaning validation is becoming more critical in downstream processes because of stricter regulations, resulting in more use of membrane chromatography. Drug production includes the processes of purifying monoclonal antibodies, separating proteins, and filtering viruses, all of which heavily rely on tangential flow filtration using membranes. As a result, we can expect significant growth in this market over the next few years, with annual increases projected to be in the double digits.
Recent Market JVs and Acquisitions:
The membrane chromatography market has undergone a few mergers & acquisitions in past years as enterprises strive to augment their market presence and leverage synergies to refine their product offerings and optimize their fiscal outcomes. Some M&A and JVs are:
- Danaher Corporation completed the acquisition of General Electric Company's Life Sciences division in March 2020, under its biopharma business, to create Cytiva. The new company is operating within Danaher's Life Sciences segment.
- MilliporeSigma, the life science business of Merck KGaA, agreed to acquire Novasep's chromatography division, which contains preparative chromatography equipment and resin, in 2021, enhancing its portfolio in downstream bioprocessing.
Recent Product Development:
- Thermo Fisher Scientific has introduced the Thermo Scientific HyPeak Chromatography System to enhance downstream bioprocessing. It will improve the efficiency of both continuous and batch processes while reducing operational costs.
- Sartorius introduced Sartobind Rapid A membranes, which enabled higher throughput and scalability in high-capacity monoclonal antibody capture.
Market Drivers:
Single-use membrane chromatography systems have gained widespread acceptance due to the minimized risk of cross-contamination, faster processing times, and lower initial capital costs. The adoption of these technologies is driven by ongoing demand for cost-effective and flexible solutions in the domain of bioprocessing. The method’s main advantage is that communication between molecules and active spots in the membrane occurs convectively through pores rather than in passive fluid inside the resin pores. The single-use nature of chromatography systems makes them contamination-proof and ideal for drug production. These qualities of membrane chromatography are driving the growth of this market significantly.
Challenges:
High expenses associated with membrane chromatography products are significant barriers to the growth of this market. Skepticism among emerging nations is the most considerable restraint to the commercial progress of membrane chromatography.
Market Segments' Analysis
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Segmentations
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List of Sub-Segments
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Segments with High Growth Opportunity
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By Component-Type Analysis
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Skids, Consumables, and Equipment.
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Skids are the most dominant, whereas consumables are exhibiting the fastest growth.
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By Process-Type Analysis
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Ion Exchange, Affinity, and HIC
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Ion exchange is both the dominant and fastest-growing process type.
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By Product-Type Analysis
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Capsules, Cartridges, Cassettes and Others
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Capsules dominate among product types and are likely to grow the fastest as well.
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By Region Analysis
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North America, Europe, Asia-Pacific, and The Rest of the World
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Asia-Pacific is the biopharma and vaccine production hub, leading the membrane chromatography market.
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By Component Type
“Skids are forecasted to emerge as the biggest whereas consumables are the most rapidly expanding category in the market during the forecast period.”
- Skids are the most critical bioprocessing hardware for housing the chromatography process and managing the flow of fluids being processed.
- Advanced control systems assure constant purification and increased efficiency, vital to meeting the biopharmaceutical industry's stringent regulatory requirements.
- The adoption of skids has increased with the bioprocessing facilities adopting scalable and reliable solutions that go along with the trends of single-use technology to augment flexibility.
By Process Type
“Ion exchange enjoys the lion’s share in the membrane chromatography market owing to its widely adopted application in the biopharma industry. It is likely to maintain its dominance and grow over the forecasted period.”
- Ion exchange has excellent resolution, which is essential for separating molecules according to charge properties. In most biopharma purification, impurities are charged with ions, which makes ion exchange the most used process type.
- Ion exchange generally employs less expensive, less complex buffers than affinity chromatography, which typically demands very expensive, ligand-specific buffers. Cost-effectiveness has also driven ion exchange to lead the market.
- Sartorius, the leader in the membrane chromatography market, has significantly focused on developing cation and anion exchange membrane filters, indicating this process type's dominance in the market.
By Product Type
“Capsules dominate in the membrane chromatography market. It is likely to maintain its dominance and grow over the forecasted period.”
- Capsule filters are compact and ready to use, making them highly convenient for labs and production facilities. They require much less time for installation or setup than cartridges or cassettes.
- The growing demand for biologics and biosimilars drives the need for membrane chromatography capsules, reflecting the trend toward more efficient and expedited purification methods.
- The use of capsules allows the processing of a much larger batch at the same turnaround time, enhancing efficiency without compromising the extent of purification.
By Region
“Asia-Pacific region is forecasted to be both biggest and fastest growing region driven by China’s dominant presence.”
- The biopharma industry is booming in Asian countries. India, China, and Japan contribute significantly to drug and vaccine production. Hence, this region shows a very optimistic scenario for the membrane chromatography market.
- Investments in healthcare infrastructure and R&D continue without hindrance in the Asia-Pacific countries. Government initiatives have supported Indigenous drug production in the post-COVID era, driving the demand for membrane chromatography.
- The region is an attractive base in terms of a cost-competitive location to manufacture chromatography products.
Key Players
It would be fair to say that the market is consolidated, with a few players contributing significantly to it. The leading players in the industry contend with several critical factors, including pricing strategies, service portfolios, regional presence, and other governing parameters. The following are the key players in the membrane chromatography market. These big players often engage in mergers and acquisition activities as a key strategy to enhance their portfolios and regional presence.
Here is the list of the Top Players (Based on Dominance)
- Sartorius AG
- Danaher (Cytiva)
- Merck KgaA
- Thermofisher Scientic
- The 3M Company
- Repligen Corp.
- Donaldson
- Shimadzu Corporation
- Agilent Technologies Inc.
- Restec Corporation
- Cole Parmer Instrument Company LLC
- GVS Group
Note: The above list does not necessarily include all the market's top players.
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Report Features
This report provides market intelligence most comprehensively. The report structure has been kept so that it offers maximum business value. It provides critical insights into market dynamics and will enable strategic decision-making for existing market players as well as those willing to enter the market. The following are the key features of the report:
- Market structure: Overview, industry life cycle analysis, supply chain analysis.
- Market environment analysis: Growth drivers and constraints, Porter’s five forces analysis, SWOT analysis.
- Market trend and forecast analysis.
- Market segment trend and forecast.
- Competitive landscape and dynamics: Market share, Service portfolio, New Product Launches, etc.
- COVID-19 impact and its recovery curve.
- Attractive market segments and associated growth opportunities.
- Emerging trends.
- Strategic growth opportunities for the existing and new players.
- Key success factors.
The membrane chromatography market is segmented into the following categories:
Membrane Chromatography Market, by Component Type
- Skids (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Consumables (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Equipment (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
Membrane Chromatography Market, by Process Type
- Ion Exchange (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Affinity (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- HIC (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
Membrane Chromatography Market by Product Type
- Capsules (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Cartridges (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Cassettes (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
- Others (Regional Analysis: North America, Europe, Asia-Pacific, and RoW)
Membrane Chromatography Market by Region
- North America (Country Analysis: The USA, Canada, and Mexico)
- Europe (Country Analysis: Germany, France, The UK, and Rest of Europe)
- Asia-Pacific (Country Analysis: Japan, China, India, and Rest of Asia-Pacific)
- Rest of the World (Country Analysis: Brazil, Saudi Arabia, and Others)
Research Methodology
- This strategic assessment report from Stratview Research provides a comprehensive analysis that reflects today’s membrane chromatography market realities and future market possibilities for the forecast period.
- The report segments and analyses the market in the most detailed manner in order to provide a panoramic view of the market.
- The vital data/information provided in the report can play a crucial role for market participants and investors in identifying the low-hanging fruits available in the market and formulating growth strategies to expedite their growth process.
- This report offers high-quality insights and is the outcome of a detailed research methodology comprising extensive secondary research, rigorous primary interviews with industry stakeholders, and validation and triangulation with Stratview Research’s internal database and statistical tools.
- More than 1,000 authenticated secondary sources, such as company annual reports, fact books, press releases, journals, investor presentations, white papers, patents, and articles, have been leveraged to gather the data.
- We conducted more than 15 detailed primary interviews with market players across the value chain in all four regions and industry experts to obtain qualitative and quantitative insights.
Customization Options
With this detailed report, Stratview Research offers one of the following free customization options to our respectable clients:
Company Profiling
- Detailed profiling of additional market players (up to three players)
- SWOT analysis of key players (up to three players)
Competitive Benchmarking
- Benchmarking of key players on the following parameters: Service portfolio, geographical reach, regional presence, and strategic alliances
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