Bone Graft And Substitute Market Report

Market Insights

"The global bone graft and substitute market size was estimated at USD 3.05 billion in 2021 and is likely to grow at a CAGR of 6.24% during 2022-2028 to reach USD 4.69 billion in 2028."

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Bone grafts are defined as implantable materials, which promote bone formation, bone healing, and osseous reconstruction due to their superior properties including osteogenic, osteoconductive, and osteoinductive. Bone grafts are also used to fill voids in case of the absence of bones.

Market Dynamics

Market Drivers

The growth of the market is driven by following factors-

• increasing incidences of musculoskeletal disorders across the globe.
• growing emphasis on the development of biocompatible synthetic bone grafts.
• surging demand for advanced products.

COVID-19 Impact

The covid-19 outbreak posed significant challenges across verticals worldwide. It impacted the growth of the bone graft and substitute market negatively as the healthcare solutions other than covid-19 treatment declined due to fear of coronavirus infection. Also, supply chain disruptions due to the imposition of lockdown affected the product availability on time and thus, affected the market growth.

Segment Analysis

Material Trends

"The allografts segment accounted for the largest market share."

The market has been bifurcated into allografts, synthetics, other. Allograft accounted for the largest share of more than 50% in 2021 and is expected to dominate during the forecast period. Their properties, such as immediate structural support and osteoconductivity are the factors propelling the growth of the market for this segment.

Application Trends

"The spinal fusion segment accounted for the largest market share."

The market is segmented into craniomaxillofacial, dental, foot & ankle, joint reconstruction, long bone & spinal fusion. Spinal fusion segment accounted for the largest share of more than 55% in 2021. The rising adoption of bone graft materials for spondylosyndesis & the rising geriatric population prone to orthopedic ailments are the major factors driving the growth of the segment.

End-Use Trends

"The hospitals segment accounted for the largest market share."

The market has been bifurcated into hospitals and dental clinics. The hospital segment accounted for the largest market share in 2021 and is projected to register significant growth during the review period. The segment can be attributed to the availability of required infrastructure, technical expertise, and skilled staff.

Regional Insights

"North America accounted for the largest market share."

The North American market accounted for the largest market share of more than 35% in 2021 and is projected to grow at a robust CAGR during the review period. This can be attributed to the rising number of people suffering from orthopedic disorders coupled with expanding geriatric populace and the presence of key market players such as Zimmer Biomet (US) and Dentsply Sirona (US). The market growth in Asia-Pacific is expected to be driven by the increasing incidence of accidental injuries and rising medical tourism in developing countries.

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Critical Questions Answered in the Report

• What are the key trends in the global market?
• How the market (and its various sub-segments) has grown in the last five years and what would be the growth rate in the next five years?
• What is the impact of COVID-19 on the global market?
• What are the key strategies adopted by the major vendors to lead in the market?
• What is the market share of the top vendors?

Key Players

The following are the key players in the bone graft and substitute market (arranged alphabetically).

• Aimedic MMT (Japan)
• B. Braun (Germany)
• Biomatlante (France)
• BioMimetic Therapeutics, LLC (US)
• Botiss medical AG (Germany)
• CryoLife, Inc. (US)
• Dentsply Sirona (US)
• DePuy Synthes (US)
• Globus Medical, Inc. (US)
• GRAFTYS (France)
• Integra Life Sciences (US)
• Johnson & Johnson (US)
• Maxigen Biotech Inc. (Taiwan)
• Medtronic plc (Ireland)
• Straumann (Switzerland)
• Zimmer Biomet (US)

Note: The above list does not necessarily include all the top players in the market.

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Recent Development

Nov 2022: Kuros Biosciences completes enrolment in Level 1 clinical study of MagnetOs Granules

Kuros Biosciences, a leader in next generation bone graft technologies, announced the completion of enrolment in the Level 1 clinical study, comparing MagnetOs Granules to the gold standard of autograft bone in patients undergoing posterolateral lumbar fusion.

Oct 2022: Bioventus Showcased Full Orthobiologics and Ultrasonic Portfolio at NASS in Chicago

Bioventus Inc., a global leader in innovations for active healing, presented its spine procedural solutions portfolio at the North American Spine Society (NASS) meeting in Chicago, October 12 through 15.

Feb 2022: Bonalive® Biomaterials Ltd. granted FDA Breakthrough Device Designation for a bone graft substitute that potentially protects against microbial colonization

The Center for Devices and Radiological Health at the Food & Drug Administration has determined that Bonalive® Orthopedics granules, made of a unique S53P4 bioactive glass, qualifies for designation as a Breakthrough Device.

Report Features

This report provides market intelligence in the most comprehensive way and the structure has been kept such that it offers maximum business value. It provides critical insights into the market dynamics and will enable strategic decision making for the existing market players as well as those willing to enter the market.

What Deliverables Will You Get in this Report?

The market is segmented into the following categories.

By Material Type

• Allografts
• Synthetics
• Other

By Application Type

• Craniomaxillofacial
• Dental
• Foot & Ankle
• Joint Reconstruction
• Long Bone
• Spinal Fusion

By End-Use Type

• Hospital
• Dental Clinic

By Region

• North America (Country Analysis: the USA, Canada, and Mexico)
• Europe (Country Analysis: Germany, France, the UK, Russia, Spain, and the Rest of Europe)
• Asia-Pacific (Country Analysis: China, Japan, India, South Korea, and the Rest of Asia-Pacific)
• Rest of the World (Sub-Region Analysis: Latin America, the Middle East, and Others)

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Research Methodology

This strategic assessment report, from Stratview Research, provides a comprehensive analysis that reflects today’s bone graft and substitute market realities and future market possibilities for the forecast period. The report segments and analyzes the market in the most detailed manner in order to provide a panoramic view of the market. The vital data/information provided in the report can play a crucial role for the market participants as well as investors in the identification of the low-hanging fruits available in the market as well as to formulate the growth strategies to expedite their growth process.

This report offers high-quality insights and is the outcome of a detailed research methodology comprising extensive secondary research, rigorous primary interviews with industry stakeholders, and validation and triangulation with Stratview Research’s internal database and statistical tools. More than 1000 authenticated secondary sources, such as company annual reports, fact books, press releases, journals, investor presentations, white papers, patents, and articles, have been leveraged to gather the data. We conducted more than 15 detailed primary interviews with the market players across the value chain in all four regions and industry experts to obtain both qualitative and quantitative insights.

Customization Option

With this detailed report, Stratview Research offers one of the following free customization options to our respectable clients:

Company Profiling

• Detailed profiling of additional market players (up to 3 players)
• SWOT analysis of key players (up to 3 players)

Competitive Benchmarking

• Benchmarking of key players on the following parameters: Product portfolio, geographical reach, regional presence, and strategic alliances.

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